BDBM50185943 3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE::3-fluoro-N-(1-(4-fluorophenyl)-3-(2-thienyl)-1H-pyrazol-5-yl)benzenesulfonamide::CHEMBL378160

SMILES: Fc1ccc(cc1)-n1nc(cc1NS(=O)(=O)c1cccc(F)c1)-c1cccs1

InChI Key: InChIKey=GULUFDCOGAXLEP-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50185943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50185943 (3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PY...) Show SMILES Fc1ccc(cc1)-n1nc(cc1NS(=O)(=O)c1cccc(F)c1)-c1cccs1 Show InChI InChI=1S/C19H13F2N3O2S2/c20-13-6-8-15(9-7-13)24-19(12-17(22-24)18-5-2-10-27-18)23-28(25,26)16-4-1-3-14(21)11-16/h1-12,23H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Effect on Gal4/PPAR-gamma-LBD construct transactivation in Huh7 cells				J Med Chem 49: 2703-12 (2006) Article DOI: 10.1021/jm051129s BindingDB Entry DOI: 10.7270/Q2736QHH
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50185943 (3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PY...) Show SMILES Fc1ccc(cc1)-n1nc(cc1NS(=O)(=O)c1cccc(F)c1)-c1cccs1 Show InChI InChI=1S/C19H13F2N3O2S2/c20-13-6-8-15(9-7-13)24-19(12-17(22-24)18-5-2-10-27-18)23-28(25,26)16-4-1-3-14(21)11-16/h1-12,23H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	512	n/a	n/a	n/a	n/a	n/a	n/a
Sookmyung Women's University Curated by ChEMBL					Assay Description Displacement of fluormone PPAR-green from N-terminal His-tagged human PPARgamma-LBD after 2 hrs by fluorescence polarization assay				Bioorg Med Chem 18: 8315-23 (2010) Article DOI: 10.1016/j.bmc.2010.09.068 BindingDB Entry DOI: 10.7270/Q25T3KQ1
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50185943 (3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PY...) Show SMILES Fc1ccc(cc1)-n1nc(cc1NS(=O)(=O)c1cccc(F)c1)-c1cccs1 Show InChI InChI=1S/C19H13F2N3O2S2/c20-13-6-8-15(9-7-13)24-19(12-17(22-24)18-5-2-10-27-18)23-28(25,26)16-4-1-3-14(21)11-16/h1-12,23H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	512	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]rosiglitazone from PPARgamma by SPA				J Med Chem 49: 2703-12 (2006) Article DOI: 10.1021/jm051129s BindingDB Entry DOI: 10.7270/Q2736QHH
					More data for this Ligand-Target Pair				3D Structure (crystal)