BDBM50186108 CHEMBL209301::N-(((1S,3R)-3-(N-benzylpivalamido)cyclohexyl)methyl)-4-fluoro-N-(3-(2-(pyrrolidin-1-yl)ethoxy)phenyl)benzamide

SMILES: CC(C)(C)C(=O)N(Cc1ccccc1)[C@@H]1CCC[C@H](CN(C(=O)c2ccc(F)cc2)c2cccc(OCCN3CCCC3)c2)C1

InChI Key: InChIKey=JEOIMYUIHSWTEE-BZKUTMRRSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50186108   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Motilin receptor (Homo sapiens (Human))	BDBM50186108 (CHEMBL209301 | N-(((1S,3R)-3-(N-benzylpivalamido)c...) Show SMILES CC(C)(C)C(=O)N(Cc1ccccc1)[C@@H]1CCC[C@H](CN(C(=O)c2ccc(F)cc2)c2cccc(OCCN3CCCC3)c2)C1 Show InChI InChI=1S/C38H48FN3O3/c1-38(2,3)37(44)42(27-29-11-5-4-6-12-29)33-14-9-13-30(25-33)28-41(36(43)31-17-19-32(39)20-18-31)34-15-10-16-35(26-34)45-24-23-40-21-7-8-22-40/h4-6,10-12,15-20,26,30,33H,7-9,13-14,21-25,27-28H2,1-3H3/t30-,33+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Activity at rabbit duodenum motilin receptor by tissue contractility assay				Bioorg Med Chem Lett 16: 3362-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.017 BindingDB Entry DOI: 10.7270/Q2XK8F5H
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50186108 (CHEMBL209301 | N-(((1S,3R)-3-(N-benzylpivalamido)c...) Show SMILES CC(C)(C)C(=O)N(Cc1ccccc1)[C@@H]1CCC[C@H](CN(C(=O)c2ccc(F)cc2)c2cccc(OCCN3CCCC3)c2)C1 Show InChI InChI=1S/C38H48FN3O3/c1-38(2,3)37(44)42(27-29-11-5-4-6-12-29)33-14-9-13-30(25-33)28-41(36(43)31-17-19-32(39)20-18-31)34-15-10-16-35(26-34)45-24-23-40-21-7-8-22-40/h4-6,10-12,15-20,26,30,33H,7-9,13-14,21-25,27-28H2,1-3H3/t30-,33+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of [125]I-motilin binding to rabbit motilin receptor				Bioorg Med Chem Lett 16: 3362-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.017 BindingDB Entry DOI: 10.7270/Q2XK8F5H
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50186108 (CHEMBL209301 | N-(((1S,3R)-3-(N-benzylpivalamido)c...) Show SMILES CC(C)(C)C(=O)N(Cc1ccccc1)[C@@H]1CCC[C@H](CN(C(=O)c2ccc(F)cc2)c2cccc(OCCN3CCCC3)c2)C1 Show InChI InChI=1S/C38H48FN3O3/c1-38(2,3)37(44)42(27-29-11-5-4-6-12-29)33-14-9-13-30(25-33)28-41(36(43)31-17-19-32(39)20-18-31)34-15-10-16-35(26-34)45-24-23-40-21-7-8-22-40/h4-6,10-12,15-20,26,30,33H,7-9,13-14,21-25,27-28H2,1-3H3/t30-,33+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	338	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Activity at human motilin receptor transfected in HEK293 cells assessed as inhibition of motilin-induced intracellular calcium mobilization				Bioorg Med Chem Lett 16: 3362-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.017 BindingDB Entry DOI: 10.7270/Q2XK8F5H
					More data for this Ligand-Target Pair