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SMILES: Clc1ccc(C[C@@H](NC(=O)CC2Cc3ccccc3N2)C(=O)N2CCN(CC2)C(CNC2CCC2)CC2CCCCC2)cc1

InChI Key: InChIKey=QDOQJKGCPCRRMX-ZZRNSSMXSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186120   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50186120
PNG
(CHEMBL380391 | N-((R)-3-(4-chlorophenyl)-1-(4-(1-(...)
Show SMILES Clc1ccc(C[C@@H](NC(=O)CC2Cc3ccccc3N2)C(=O)N2CCN(CC2)C(CNC2CCC2)CC2CCCCC2)cc1
Show InChI InChI=1S/C36H50ClN5O2/c37-29-15-13-27(14-16-29)22-34(40-35(43)24-31-23-28-9-4-5-12-33(28)39-31)36(44)42-19-17-41(18-20-42)32(25-38-30-10-6-11-30)21-26-7-2-1-3-8-26/h4-5,9,12-16,26,30-32,34,38-39H,1-3,6-8,10-11,17-25H2,(H,40,43)/t31?,32?,34-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

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Similars
Article
PubMed
 12n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125]I-NDP-alpha-MSH binding to human MC4R transfected in HEK293 cells

Bioorg Med Chem Lett 16: 3449-53 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.002
BindingDB Entry DOI: 10.7270/Q2ST7PFS
More data for this
Ligand-Target Pair