BDBM50186146 3-[1-(cyclobutylamino)-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl]-7-[(methylsulfamoyl)amino]-2H-1,2,4-benzothiadiazine-1,1-dione::CHEMBL210693

SMILES: CNS(=O)(=O)Nc1ccc2N=C(NS(=O)(=O)c2c1)c1c(O)c2ccccc2n(NC2CCC2)c1=O

InChI Key: InChIKey=ZQNFIPVEPYTGOP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186146   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50186146 (3-[1-(cyclobutylamino)-4-hydroxy-2-oxo-1,2-dihydro...) Show SMILES CNS(=O)(=O)Nc1ccc2N=C(NS(=O)(=O)c2c1)c1c(O)c2ccccc2n(NC2CCC2)c1=O |c:10| Show InChI InChI=1S/C21H22N6O6S2/c1-22-35(32,33)25-13-9-10-15-17(11-13)34(30,31)26-20(23-15)18-19(28)14-7-2-3-8-16(14)27(21(18)29)24-12-5-4-6-12/h2-3,7-12,22,24-25,28H,4-6H2,1H3,(H,23,26)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of HCV 1a NS5B RNA polymerase				Bioorg Med Chem Lett 16: 3367-70 (2006) Article DOI: 10.1016/j.bmcl.2006.04.015 BindingDB Entry DOI: 10.7270/Q2P26XQC
					More data for this Ligand-Target Pair