BDBM50186242 (S)-N-(1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2,5-dioxopyrrolidin-3-yl)acetamide::CHEMBL210157

SMILES: COc1ccccc1N1CCN(CCCCN2C(=O)C[C@H](NC(C)=O)C2=O)CC1

InChI Key: InChIKey=GKLSRXWQPMCFDA-KRWDZBQOSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186242   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50186242 ((S)-N-(1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)but...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)C[C@H](NC(C)=O)C2=O)CC1 |r| Show InChI InChI=1S/C21H30N4O4/c1-16(26)22-17-15-20(27)25(21(17)28)10-6-5-9-23-11-13-24(14-12-23)18-7-3-4-8-19(18)29-2/h3-4,7-8,17H,5-6,9-15H2,1-2H3,(H,22,26)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane				Eur J Med Chem 44: 800-8 (2009) Article DOI: 10.1016/j.ejmech.2008.05.021 BindingDB Entry DOI: 10.7270/Q20Z7468
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50186242 ((S)-N-(1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)but...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)C[C@H](NC(C)=O)C2=O)CC1 |r| Show InChI InChI=1S/C21H30N4O4/c1-16(26)22-17-15-20(27)25(21(17)28)10-6-5-9-23-11-13-24(14-12-23)18-7-3-4-8-19(18)29-2/h3-4,7-8,17H,5-6,9-15H2,1-2H3,(H,22,26)/t17-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier I et II Curated by ChEMBL					Assay Description Affinity for 5HT1A receptor				Bioorg Med Chem Lett 16: 3406-10 (2006) Article DOI: 10.1016/j.bmcl.2006.04.035 BindingDB Entry DOI: 10.7270/Q2542N6V
					More data for this Ligand-Target Pair