BDBM50186290 3-ethyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine::CHEMBL207078

SMILES: CCN1CCc2ccc(OCCCN3CCCCC3)cc2CC1

InChI Key: InChIKey=XCDYOQOTPFDKPW-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50186290   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186290 (3-ethyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tetr...) Show SMILES CCN1CCc2ccc(OCCCN3CCCCC3)cc2CC1 Show InChI InChI=1S/C20H32N2O/c1-2-21-14-9-18-7-8-20(17-19(18)10-15-21)23-16-6-13-22-11-4-3-5-12-22/h7-8,17H,2-6,9-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50186290 (3-ethyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tetr...) Show SMILES CCN1CCc2ccc(OCCCN3CCCCC3)cc2CC1 Show InChI InChI=1S/C20H32N2O/c1-2-21-14-9-18-7-8-20(17-19(18)10-15-21)23-16-6-13-22-11-4-3-5-12-22/h7-8,17H,2-6,9-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BIOPROJET-BIOTECH Curated by ChEMBL					Assay Description Binding affinity to histamine H3 receptor (unknown origin)				Bioorg Med Chem 21: 4526-9 (2013) Article DOI: 10.1016/j.bmc.2013.05.035 BindingDB Entry DOI: 10.7270/Q2J9699Q
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50186290 (3-ethyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tetr...) Show SMILES CCN1CCc2ccc(OCCCN3CCCCC3)cc2CC1 Show InChI InChI=1S/C20H32N2O/c1-2-21-14-9-18-7-8-20(17-19(18)10-15-21)23-16-6-13-22-11-4-3-5-12-22/h7-8,17H,2-6,9-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor				Bioorg Med Chem Lett 16: 3415-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07
					More data for this Ligand-Target Pair