BDBM50186338 CHEMBL3823329

SMILES: CCc1cnc(nc1)N1CCC(CC1)n1ncc2cc(ncc12)-c1cc(F)c(cc1F)C(=O)NCCO

InChI Key: InChIKey=WPDWJHNPVLRNCW-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186338   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50186338 (CHEMBL3823329) Show SMILES CCc1cnc(nc1)N1CCC(CC1)n1ncc2cc(ncc12)-c1cc(F)c(cc1F)C(=O)NCCO Show InChI InChI=1S/C26H27F2N7O2/c1-2-16-12-31-26(32-13-16)34-6-3-18(4-7-34)35-24-15-30-23(9-17(24)14-33-35)19-10-22(28)20(11-21(19)27)25(37)29-5-8-36/h9-15,18,36H,2-8H2,1H3,(H,29,37)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay				Bioorg Med Chem Lett 26: 3441-6 (2016) BindingDB Entry DOI: 10.7270/Q2XW4MRS
					More data for this Ligand-Target Pair