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SMILES: CCc1cnc(nc1)N1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(cc1F)S(C)(=O)=O

InChI Key: InChIKey=JRWQQVIJNHRANF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186339   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucose-dependent insulinotropic receptor


(Homo sapiens (Human))		BDBM50186339
PNG
(CHEMBL3823780)
Show SMILES CCc1cnc(nc1)N1CCC(CC1)n1ncc2cc(ncc12)-c1ccc(cc1F)S(C)(=O)=O
Show InChI InChI=1S/C24H25FN6O2S/c1-3-16-12-27-24(28-13-16)30-8-6-18(7-9-30)31-23-15-26-22(10-17(23)14-29-31)20-5-4-19(11-21(20)25)34(2,32)33/h4-5,10-15,18H,3,6-9H2,1-2H3
UniProtKB/SwissProt

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PC cid
PC sid
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Similars
PubMed
n/an/an/an/a 4n/an/an/an/a



Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in Flp-In-T-Rex-HEK293 cells after 30 mins by cAMP accumulation assay

Bioorg Med Chem Lett 26: 3441-6 (2016)


BindingDB Entry DOI: 10.7270/Q2XW4MRS
More data for this
Ligand-Target Pair