BDBM50186357 2-(5-(2-methoxyphenoxy)-1H-indazol-3-yl)-5-(4-(piperidin-1-yl)piperidin-1-yl)-1H-benzo[d]imidazole::CHEMBL211508

SMILES: COc1ccccc1Oc1ccc2[nH]nc(-c3nc4ccc(cc4[nH]3)N3CCC(CC3)N3CCCCC3)c2c1

InChI Key: InChIKey=WZFSTZPVDMXXKL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186357   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50186357 (2-(5-(2-methoxyphenoxy)-1H-indazol-3-yl)-5-(4-(pip...) Show SMILES COc1ccccc1Oc1ccc2[nH]nc(-c3nc4ccc(cc4[nH]3)N3CCC(CC3)N3CCCCC3)c2c1 Show InChI InChI=1S/C31H34N6O2/c1-38-28-7-3-4-8-29(28)39-23-10-12-25-24(20-23)30(35-34-25)31-32-26-11-9-22(19-27(26)33-31)37-17-13-21(14-18-37)36-15-5-2-6-16-36/h3-4,7-12,19-21H,2,5-6,13-18H2,1H3,(H,32,33)(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibition of c-ABL				Bioorg Med Chem Lett 16: 3789-92 (2006) Article DOI: 10.1016/j.bmcl.2006.04.043 BindingDB Entry DOI: 10.7270/Q2HD7WG3
					More data for this Ligand-Target Pair