BDBM50186399 3-(4-(5-(3-cyanophenyl)-1,3,4-thiadiazol-2-yl)-3-methylphenyl)propanoic acid::CHEMBL207716

SMILES: Cc1cc(CCC(O)=O)ccc1-c1nnc(s1)-c1cccc(c1)C#N

InChI Key: InChIKey=QSKRBYXAPPKDJS-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186399   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50186399 (3-(4-(5-(3-cyanophenyl)-1,3,4-thiadiazol-2-yl)-3-m...) Show SMILES Cc1cc(CCC(O)=O)ccc1-c1nnc(s1)-c1cccc(c1)C#N Show InChI InChI=1S/C19H15N3O2S/c1-12-9-13(6-8-17(23)24)5-7-16(12)19-22-21-18(25-19)15-4-2-3-14(10-15)11-20/h2-5,7,9-10H,6,8H2,1H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Agonist activity at S1P1 receptor assessed as induction of [35S]GTPgammaS binding				Bioorg Med Chem Lett 16: 3684-7 (2006) Article DOI: 10.1016/j.bmcl.2006.04.064 BindingDB Entry DOI: 10.7270/Q2HD7V7J
					More data for this Ligand-Target Pair