BDBM50186419 (R)-2-amino-N-(4-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-ylamino)phenylsulfonyl)-3-hydroxypropanamide::CHEMBL212264

SMILES: N[C@H](CO)C(=O)NS(=O)(=O)c1ccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)cc1

InChI Key: InChIKey=LNWXGYVVZJDLCP-CYBMUJFWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186419   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50186419 ((R)-2-amino-N-(4-(5-amino-1-(2,6-difluorobenzoyl)-...) Show SMILES N[C@H](CO)C(=O)NS(=O)(=O)c1ccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)cc1 Show InChI InChI=1S/C18H17F2N7O5S/c19-11-2-1-3-12(20)14(11)16(30)27-17(22)24-18(25-27)23-9-4-6-10(7-5-9)33(31,32)26-15(29)13(21)8-28/h1-7,13,28H,8,21H2,(H,26,29)(H3,22,23,24,25)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development LLC Curated by ChEMBL					Assay Description Inhibition of CDK2				Bioorg Med Chem Lett 16: 3639-41 (2006) Article DOI: 10.1016/j.bmcl.2006.04.071 BindingDB Entry DOI: 10.7270/Q2CN73H6
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50186419 ((R)-2-amino-N-(4-(5-amino-1-(2,6-difluorobenzoyl)-...) Show SMILES N[C@H](CO)C(=O)NS(=O)(=O)c1ccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)cc1 Show InChI InChI=1S/C18H17F2N7O5S/c19-11-2-1-3-12(20)14(11)16(30)27-17(22)24-18(25-27)23-9-4-6-10(7-5-9)33(31,32)26-15(29)13(21)8-28/h1-7,13,28H,8,21H2,(H,26,29)(H3,22,23,24,25)/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development LLC Curated by ChEMBL					Assay Description Inhibition of CDK1				Bioorg Med Chem Lett 16: 3639-41 (2006) Article DOI: 10.1016/j.bmcl.2006.04.071 BindingDB Entry DOI: 10.7270/Q2CN73H6
					More data for this Ligand-Target Pair