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SMILES: Cc1cc(COc2ccc(cc2)C(N)=O)c2c(N)c(sc2n1)C(N)=O

InChI Key: InChIKey=BZVQREJPPVBQCO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186653   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Inhibitor of nuclear factor kappa-B kinase subunit beta


(Homo sapiens (Human))		BDBM50186653
PNG
(CHEMBL207238 | amino-4-(4-carbamoyl-phenoxymethyl)...)
Show SMILES Cc1cc(COc2ccc(cc2)C(N)=O)c2c(N)c(sc2n1)C(N)=O
Show InChI InChI=1S/C17H16N4O3S/c1-8-6-10(7-24-11-4-2-9(3-5-11)15(19)22)12-13(18)14(16(20)23)25-17(12)21-8/h2-6H,7,18H2,1H3,(H2,19,22)(H2,20,23)
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Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of IKK beta

J Med Chem 49: 2898-908 (2006)


Article DOI: 10.1021/jm0510979
BindingDB Entry DOI: 10.7270/Q2TQ614S
More data for this
Ligand-Target Pair