BDBM50186676 (+/-)-3-difluoromethyl-7-bromo-1,2,3,4-tetrahydroisoquinoline::CHEMBL381297

SMILES: FC(F)C1Cc2ccc(Br)cc2CN1

InChI Key: InChIKey=ARNKQLYWYANBBE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186676   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50186676 ((+/-)-3-difluoromethyl-7-bromo-1,2,3,4-tetrahydroi...) Show SMILES FC(F)C1Cc2ccc(Br)cc2CN1 Show InChI InChI=1S/C10H10BrF2N/c11-8-2-1-6-4-9(10(12)13)14-5-7(6)3-8/h1-3,9-10,14H,4-5H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Binding affinity to human PNMT				J Med Chem 49: 2939-52 (2006) Article DOI: 10.1021/jm051262k BindingDB Entry DOI: 10.7270/Q2K64HQ3
					More data for this Ligand-Target Pair