BDBM50186998 3-(2-hydroxy-5-nitrophenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione::CHEMBL209858

SMILES: Oc1ccc(cc1Nc1c(Nc2ccccc2)c(=O)c1=O)[N+]([O-])=O

InChI Key: InChIKey=RHCXHYFIOPFDIE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50186998 (3-(2-hydroxy-5-nitrophenylamino)-4-(phenylamino)cy...) Show SMILES Oc1ccc(cc1Nc1c(Nc2ccccc2)c(=O)c1=O)[N+]([O-])=O Show InChI InChI=1S/C16H11N3O5/c20-12-7-6-10(19(23)24)8-11(12)18-14-13(15(21)16(14)22)17-9-4-2-1-3-5-9/h1-8,17-18,20H	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Drug Discovery, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells				Bioorg Med Chem Lett 16: 4107-10 (2006) Article DOI: 10.1016/j.bmcl.2006.04.082 BindingDB Entry DOI: 10.7270/Q24X57DB
					More data for this Ligand-Target Pair