BDBM50187006 3-(2-hydroxyphenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione::CHEMBL424694

SMILES: Oc1ccccc1Nc1c(Nc2ccccc2)c(=O)c1=O

InChI Key: InChIKey=MTUDRPBFVNRFDO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187006   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50187006 (3-(2-hydroxyphenylamino)-4-(phenylamino)cyclobut-3...) Show SMILES Oc1ccccc1Nc1c(Nc2ccccc2)c(=O)c1=O Show InChI InChI=1S/C16H12N2O3/c19-12-9-5-4-8-11(12)18-14-13(15(20)16(14)21)17-10-6-2-1-3-7-10/h1-9,17-19H	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	235	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [125I]IL8 from human recombinant CXCR2 expressed in CHO cells				Bioorg Med Chem Lett 17: 1713-7 (2007) Article DOI: 10.1016/j.bmcl.2006.12.067 BindingDB Entry DOI: 10.7270/Q2Z320GC
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50187006 (3-(2-hydroxyphenylamino)-4-(phenylamino)cyclobut-3...) Show SMILES Oc1ccccc1Nc1c(Nc2ccccc2)c(=O)c1=O Show InChI InChI=1S/C16H12N2O3/c19-12-9-5-4-8-11(12)18-14-13(15(20)16(14)21)17-10-6-2-1-3-7-10/h1-9,17-19H	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	476	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Drug Discovery, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells				Bioorg Med Chem Lett 16: 4107-10 (2006) Article DOI: 10.1016/j.bmcl.2006.04.082 BindingDB Entry DOI: 10.7270/Q24X57DB
					More data for this Ligand-Target Pair