BDBM50187008 (R)-3-(2-(2,3-dihydro-1H-inden-1-ylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide::CHEMBL213147

SMILES: CN(C)C(=O)c1cccc(Nc2c(N[C@@H]3CCc4ccccc34)c(=O)c2=O)c1O

InChI Key: InChIKey=JZDCFPKBWIRDEU-OAHLLOKOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187008   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50187008 ((R)-3-(2-(2,3-dihydro-1H-inden-1-ylamino)-3,4-diox...) Show SMILES CN(C)C(=O)c1cccc(Nc2c(N[C@@H]3CCc4ccccc34)c(=O)c2=O)c1O Show InChI InChI=1S/C22H21N3O4/c1-25(2)22(29)14-8-5-9-16(19(14)26)24-18-17(20(27)21(18)28)23-15-11-10-12-6-3-4-7-13(12)15/h3-9,15,23-24,26H,10-11H2,1-2H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	548	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Drug Discovery, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells				Bioorg Med Chem Lett 16: 4107-10 (2006) Article DOI: 10.1016/j.bmcl.2006.04.082 BindingDB Entry DOI: 10.7270/Q24X57DB
					More data for this Ligand-Target Pair