BDBM50187009 3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-4-hydroxybenzonitrile::CHEMBL378503

SMILES: Oc1ccc(cc1Nc1c(Nc2ccccc2)c(=O)c1=O)C#N

InChI Key: InChIKey=IDQDWQAMRXRUCG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50187009 (3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-...) Show SMILES Oc1ccc(cc1Nc1c(Nc2ccccc2)c(=O)c1=O)C#N Show InChI InChI=1S/C17H11N3O3/c18-9-10-6-7-13(21)12(8-10)20-15-14(16(22)17(15)23)19-11-4-2-1-3-5-11/h1-8,19-21H	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Drug Discovery, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells				Bioorg Med Chem Lett 16: 4107-10 (2006) Article DOI: 10.1016/j.bmcl.2006.04.082 BindingDB Entry DOI: 10.7270/Q24X57DB
					More data for this Ligand-Target Pair