BDBM50187012 CHEMBL436940::N-benzyl-3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxybenzamide

SMILES: Oc1c(Nc2c(Nc3ccccc3)c(=O)c2=O)cccc1C(=O)NCc1ccccc1

InChI Key: InChIKey=KSNDKDIEKLHSSC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187012   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50187012 (CHEMBL436940 | N-benzyl-3-(3,4-dioxo-2-(phenylamin...) Show SMILES Oc1c(Nc2c(Nc3ccccc3)c(=O)c2=O)cccc1C(=O)NCc1ccccc1 Show InChI InChI=1S/C24H19N3O4/c28-21-17(24(31)25-14-15-8-3-1-4-9-15)12-7-13-18(21)27-20-19(22(29)23(20)30)26-16-10-5-2-6-11-16/h1-13,26-28H,14H2,(H,25,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	139	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Drug Discovery, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells				Bioorg Med Chem Lett 16: 4107-10 (2006) Article DOI: 10.1016/j.bmcl.2006.04.082 BindingDB Entry DOI: 10.7270/Q24X57DB
					More data for this Ligand-Target Pair