BDBM50187050 (S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(3-(dimethylamino)propylideneamino)-2-phenylacetamide::CHEMBL209411

SMILES: CN(C)CCC=N[C@H](C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ccccc1

InChI Key: InChIKey=DMDOKFVLDOQFCF-IBGZPJMESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187050   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50187050 ((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(3-(dimet...) Show SMILES CN(C)CCC=N[C@H](C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ccccc1 |w:5.4| Show InChI InChI=1S/C22H23F6N3O/c1-31(2)10-6-9-29-19(16-7-4-3-5-8-16)20(32)30-14-15-11-17(21(23,24)25)13-18(12-15)22(26,27)28/h3-5,7-9,11-13,19H,6,10,14H2,1-2H3,(H,30,32)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]MCP1 from human CCR2 expressed in CHO cells				Bioorg Med Chem Lett 16: 3735-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.045 BindingDB Entry DOI: 10.7270/Q2N01645
					More data for this Ligand-Target Pair