BDBM50187218 (S)-1-(3,4,5-trichloro-2-hydroxyphenylsulfonyl)pyrrolidine-2-carboxylic acid::CHEMBL210597

SMILES: OC(=O)[C@@H]1CCCN1S(=O)(=O)c1cc(Cl)c(Cl)c(Cl)c1O

InChI Key: InChIKey=SMIZKRHOEQTUGE-LURJTMIESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187218   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50187218 ((S)-1-(3,4,5-trichloro-2-hydroxyphenylsulfonyl)pyr...) Show SMILES OC(=O)[C@@H]1CCCN1S(=O)(=O)c1cc(Cl)c(Cl)c(Cl)c1O Show InChI InChI=1S/C11H10Cl3NO5S/c12-5-4-7(10(16)9(14)8(5)13)21(19,20)15-3-1-2-6(15)11(17)18/h4,6,16H,1-3H2,(H,17,18)/t6-/m0/s1	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Cytotoxicity against human Huh7 cell line containing HCV genotype 1b replicon				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50187218 ((S)-1-(3,4,5-trichloro-2-hydroxyphenylsulfonyl)pyr...) Show SMILES OC(=O)[C@@H]1CCCN1S(=O)(=O)c1cc(Cl)c(Cl)c(Cl)c1O Show InChI InChI=1S/C11H10Cl3NO5S/c12-5-4-7(10(16)9(14)8(5)13)21(19,20)15-3-1-2-6(15)11(17)18/h4,6,16H,1-3H2,(H,17,18)/t6-/m0/s1	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Cytotoxicity against human Huh7 cell line containing HCV genotype 1b replicon				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair