BDBM50187227 (S)-1-(2-acetamido-5-chloro-4-methylphenylsulfonyl)pyrrolidine-2-carboxylic acid::CHEMBL379117

SMILES: CC(=O)Nc1cc(C)c(Cl)cc1S(=O)(=O)N1CCC[C@H]1C(O)=O

InChI Key: InChIKey=UZBUVQNUYFWXNE-LBPRGKRZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187227   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50187227 ((S)-1-(2-acetamido-5-chloro-4-methylphenylsulfonyl...) Show SMILES CC(=O)Nc1cc(C)c(Cl)cc1S(=O)(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C14H17ClN2O5S/c1-8-6-11(16-9(2)18)13(7-10(8)15)23(21,22)17-5-3-4-12(17)14(19)20/h6-7,12H,3-5H2,1-2H3,(H,16,18)(H,19,20)/t12-/m0/s1	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair