BDBM50187276 (2R,5S)-1-(2-(2-phenylpropan-2-ylamino)acetyl)pyrrolidine-2,5-dicarbonitrile::CHEMBL210259

SMILES: CC(C)(NCC(=O)N1[C@@H](CC[C@@H]1C#N)C#N)c1ccccc1

InChI Key: InChIKey=HNYKHFDVHONSNU-GASCZTMLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187276   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50187276 ((2R,5S)-1-(2-(2-phenylpropan-2-ylamino)acetyl)pyrr...) Show SMILES CC(C)(NCC(=O)N1[C@@H](CC[C@@H]1C#N)C#N)c1ccccc1 Show InChI InChI=1S/C17H20N4O/c1-17(2,13-6-4-3-5-7-13)20-12-16(22)21-14(10-18)8-9-15(21)11-19/h3-7,14-15,20H,8-9,12H2,1-2H3/t14-,15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	261	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP4				J Med Chem 49: 3068-76 (2006) Article DOI: 10.1021/jm0600085 BindingDB Entry DOI: 10.7270/Q2BG2NM7
					More data for this Ligand-Target Pair