BDBM50187366 (5-Methoxy-1H-indol-2-yl)-(6-methyl-1H-indol-2-yl)-methanone::CHEMBL380038

SMILES: COc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccc(C)cc2[nH]1

InChI Key: InChIKey=QXSIQVZHEWNALE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187366   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50187366 ((5-Methoxy-1H-indol-2-yl)-(6-methyl-1H-indol-2-yl)...) Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccc(C)cc2[nH]1 Show InChI InChI=1S/C19H16N2O2/c1-11-3-4-12-9-17(21-16(12)7-11)19(22)18-10-13-8-14(23-2)5-6-15(13)20-18/h3-10,20-21H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of endogenous FLT3 in EOL1 cells				J Med Chem 49: 3101-15 (2006) Article DOI: 10.1021/jm058033i BindingDB Entry DOI: 10.7270/Q26T0M7B
					More data for this Ligand-Target Pair
PDGFR-beta/Platelet-derived growth factor receptor alpha (Mus musculus (mouse))	BDBM50187366 ((5-Methoxy-1H-indol-2-yl)-(6-methyl-1H-indol-2-yl)...) Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccc(C)cc2[nH]1 Show InChI InChI=1S/C19H16N2O2/c1-11-3-4-12-9-17(21-16(12)7-11)19(22)18-10-13-8-14(23-2)5-6-15(13)20-18/h3-10,20-21H,1-2H3	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of endogenous PDGFR in Swiss3T3 fibroblasts				J Med Chem 49: 3101-15 (2006) Article DOI: 10.1021/jm058033i BindingDB Entry DOI: 10.7270/Q26T0M7B
					More data for this Ligand-Target Pair