BDBM50187613 5-(4-phenyl-1,2,3-triazol-1-yl)-1,3-diphenyl-1H-pyrazole::CHEMBL210312

SMILES: c1c(nn(c1-n1cc(nn1)-c1ccccc1)-c1ccccc1)-c1ccccc1

InChI Key: InChIKey=VAULVTRHVWLGKU-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187613   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50187613 (5-(4-phenyl-1,2,3-triazol-1-yl)-1,3-diphenyl-1H-py...) Show SMILES c1c(nn(c1-n1cc(nn1)-c1ccccc1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C23H17N5/c1-4-10-18(11-5-1)21-16-23(28(25-21)20-14-8-3-9-15-20)27-17-22(24-26-27)19-12-6-2-7-13-19/h1-17H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.88E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Displacement of [3H]methoxyPEPy from rat mGluR5 expressed in HEK293 cells				J Med Chem 49: 3332-44 (2006) Article DOI: 10.1021/jm051252j BindingDB Entry DOI: 10.7270/Q2PR7VK1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50187613 (5-(4-phenyl-1,2,3-triazol-1-yl)-1,3-diphenyl-1H-py...) Show SMILES c1c(nn(c1-n1cc(nn1)-c1ccccc1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C23H17N5/c1-4-10-18(11-5-1)21-16-23(28(25-21)20-14-8-3-9-15-20)27-17-22(24-26-27)19-12-6-2-7-13-19/h1-17H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Activity at mGluR5 assessed as potentiation of glutamate-induced calcium flux in rat astrocytes				J Med Chem 49: 3332-44 (2006) Article DOI: 10.1021/jm051252j BindingDB Entry DOI: 10.7270/Q2PR7VK1
					More data for this Ligand-Target Pair