BDBM50187683 CHEMBL1186488
SMILES: COc1cc(CCN(C)C)c2ccc3ccccc3c2c1OC
InChI Key: InChIKey=UZZFAUDNCIFFPM-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50187683 (CHEMBL1186488) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 321 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Valencia Curated by ChEMBL | Assay Description Displacement of [3H]-raclopride from D2 receptor of Wistar rat striatal membranes after 1 hr by liquid scintillation counting | Bioorg Med Chem Lett 23: 4824-7 (2013) Article DOI: 10.1016/j.bmcl.2013.06.078 BindingDB Entry DOI: 10.7270/Q2BK1G9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50187683 (CHEMBL1186488) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 323 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Valencia Curated by ChEMBL | Assay Description Displacement of [3H]-raclopride from D2 receptor of Wistar rat striatal membranes after 1 hr by liquid scintillation counting | Bioorg Med Chem Lett 23: 4824-7 (2013) Article DOI: 10.1016/j.bmcl.2013.06.078 BindingDB Entry DOI: 10.7270/Q2BK1G9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50187683 (CHEMBL1186488) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 2.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Valencia Curated by ChEMBL | Assay Description Displacement of [3H]-SCH23390 from D1 receptor of Wistar rat striatal membranes after 1 hr by liquid scintillation counting | Bioorg Med Chem Lett 23: 4824-7 (2013) Article DOI: 10.1016/j.bmcl.2013.06.078 BindingDB Entry DOI: 10.7270/Q2BK1G9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50187683 (CHEMBL1186488) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 2.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Valencia Curated by ChEMBL | Assay Description Displacement of [3H]-SCH23390 from D1 receptor of Wistar rat striatal membranes after 1 hr by liquid scintillation counting | Bioorg Med Chem Lett 23: 4824-7 (2013) Article DOI: 10.1016/j.bmcl.2013.06.078 BindingDB Entry DOI: 10.7270/Q2BK1G9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Butyrylcholinesterase (BuChE) (Equus caballus (Horse)) | BDBM50187683 (CHEMBL1186488) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Malaya Curated by ChEMBL | Assay Description Inhibition of equine serum BChE preincubated for 15 mins followed by addition of S-butyrylthiocholine chloride as substrate measured after 30 mins by... | Bioorg Med Chem 24: 4464-4469 (2016) BindingDB Entry DOI: 10.7270/Q2MG7RFM | |||||||||||
More data for this Ligand-Target Pair |