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BDBM50187708 CHEMBL3827374

SMILES: NC(=N)c1ccc2[nH]c(cc2c1)-c1cc(ccc1O)-c1ccccc1

InChI Key: InChIKey=DWFABQLVSHRVRB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187708   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepsin


(Homo sapiens (human))
BDBM50187708
PNG
(CHEMBL3827374)
Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cc(ccc1O)-c1ccccc1
Show InChI InChI=1S/C21H17N3O/c22-21(23)15-6-8-18-16(10-15)12-19(24-18)17-11-14(7-9-20(17)25)13-4-2-1-3-5-13/h1-12,24-25H,(H3,22,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 8.90E+3n/an/an/an/an/an/a



Korea University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human hepsin using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair