BDBM50187716 CHEMBL3735648
SMILES: CC1(C)c2[nH]c3cc(ccc3c2C(=O)c2ccc(cc12)C1CCN(CC2CCOCC2)CC1)C#N
InChI Key: InChIKey=VWCZORWQNKCYGE-UHFFFAOYSA-N
Data: 32 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of N-terminal His6-tagged recombinant human ALK (1058 residues) expressed in insect Sf21 cells using poly(Glu,Tyr)4:1 as substrate incubat... | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of gatekeeper ALK L1196M mutant (unknown origin) using poly (Glu, Tyr)4:1 substrate incubated for 60 mins by ELISA | Eur J Med Chem 105: 39-56 (2015) Article DOI: 10.1016/j.ejmech.2015.10.005 BindingDB Entry DOI: 10.7270/Q2BV7KM3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukocyte tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant LTK (unknown origin) using poly(Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISA | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase ROS (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant ROS1 (unknown origin) using poly(Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISA | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Insulin-like growth factor I receptor (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of N-terminal His6-tagged recombinant human IGF-1R (959 residues) expressed in insect Sf21 cells using poly(Glu,Tyr)4:1 as substrate incub... | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant human AXL using poly(Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISA | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of N-terminal His6-tagged recombinant human TYRO3 (451 residues) expressed in insect Sf21 cells using poly(Glu,Tyr)4:1 as substrate incuba... | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage-stimulating protein receptor (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of N-terminal His6-tagged recombinant human Ron (983 residues) expressed in insect Sf21 cells using poly(Glu,Tyr)4:1 as substrate incubate... | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 104 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of N-terminal His6-tagged recombinant human KDR (790 residues) expressed in insect Sf21 cells using poly(Glu,Tyr)4:1 as substrate incubate... | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor alpha (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 402 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of N-terminal His6-tagged recombinant human PDGFRalpha (550 residues) expressed in insect Sf21 cells using poly(Glu,Tyr)4:1 as substrate i... | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of N-terminal His6-tagged recombinant human PDGFRbeta (557 residues) expressed in insect Sf21 cells using poly(Glu,Tyr)4:1 as substrate in... | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor protein-tyrosine kinase erbB-4 (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 213 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of N-terminal His6-tagged recombinant human ErbB4 (709 to 991 residues) expressed in insect Sf21 cells using poly(Glu,Tyr)4:1 as substrate... | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 159 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of N-terminal GST-tagged recombinant human FLT1 (783 residues) expressed in insect Sf21 cells using poly(Glu,Tyr)4:1 as substrate incubate... | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of N-terminal GST-tagged recombinant human FLT3 (564 residues) expressed in insect Sf21 cells using poly(Glu,Tyr)4:1 as substrate incubate... | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant human c-Src expressed in insect Sf9 cells using poly(Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISA | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of N-terminal GST-tagged recombinant human EGFR T790M/L858R double mutant (696 residues) expressed in insect Sf21 cells using poly(Glu,Tyr... | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Mus musculus) | BDBM50187716 (CHEMBL3735648) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of N-terminal His6-tagged recombinant mouse ABL (27 to 1123 residues) expressed in insect Sf21 cells using poly(Glu,Tyr)4:1 as substrate i... | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of N-terminal GST-tagged recombinant human FGFR1 (456 to 765 residues) expressed in insect Sf21 cells using poly(Glu,Tyr)4:1 as substrate ... | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of human ErbB2 using poly(Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISA | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of N-terminal GST-tagged recombinant human c-Kit (544 residues) expressed in insect Sf21 cells using poly(Glu,Tyr)4:1 as substrate incubat... | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of wild type N-terminal GST-tagged recombinant human RET (658 residues) expressed in insect Sf21 cells using poly(Glu,Tyr)4:1 as substrate... | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of N-terminal GST-tagged recombinant human RET V804M mutant (658 residues) expressed in insect Sf21 cells using poly(Glu,Tyr)4:1 as substr... | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of ALK expressed in human NCI-H3122 cells assessed as cell growth inhibition after 72 hrs by SRB/CCK-8 assay | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant ALK L1196M mutant (unknown origin) using poly(Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISA | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant ALK C1156Y mutant (unknown origin) using poly(Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISA | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant ALK F1174L mutant (unknown origin) using poly(Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISA | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant ALK G1269A mutant (unknown origin) using poly(Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISA | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant ALK R1275Q mutant (unknown origin) using poly(Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISA | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant ALK T1151ins mutant (unknown origin) using poly(Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISA | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae) | BDBM50187716 (CHEMBL3735648) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ocean University of China Curated by ChEMBL | Assay Description Inhibition of human ERG | Bioorg Med Chem Lett 26: 5399-5402 (2016) Article DOI: 10.1016/j.bmcl.2016.10.039 BindingDB Entry DOI: 10.7270/Q22809JW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant ALK (unknown origin) using poly (Glu, Tyr)4:1 substrate incubated for 60 mins by ELISA | Eur J Med Chem 105: 39-56 (2015) Article DOI: 10.1016/j.ejmech.2015.10.005 BindingDB Entry DOI: 10.7270/Q2BV7KM3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50187716 (CHEMBL3735648) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of N-terminal His6-tagged recombinant human c-Met (974 residues) expressed in insect Sf21 cells using poly(Glu,Tyr)4:1 as substrate incuba... | Eur J Med Chem 118: 244-9 (2016) BindingDB Entry DOI: 10.7270/Q2Q81G02 | |||||||||||
More data for this Ligand-Target Pair |