BDBM50187747 3-(1-(5-(piperidin-1-yl)pentyl)piperidin-4-yl)-1H-indole dihydrochloride::CHEMBL537651

SMILES: C(CCN1CCCCC1)CCN1CCC(CC1)c1c[nH]c2ccccc12

InChI Key: InChIKey=FRIXRRJXNBEHHG-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50187747   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat))	BDBM50187747 (3-(1-(5-(piperidin-1-yl)pentyl)piperidin-4-yl)-1H-...) Show SMILES C(CCN1CCCCC1)CCN1CCC(CC1)c1c[nH]c2ccccc12 Show InChI InChI=1S/C23H35N3/c1-5-13-25(14-6-1)15-7-2-8-16-26-17-11-20(12-18-26)22-19-24-23-10-4-3-9-21(22)23/h3-4,9-10,19-20,24H,1-2,5-8,11-18H2	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from adrenergic alpha-1B receptor in rat liver membranes				Bioorg Med Chem Lett 16: 4045-7 (2006) Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50187747 (3-(1-(5-(piperidin-1-yl)pentyl)piperidin-4-yl)-1H-...) Show SMILES C(CCN1CCCCC1)CCN1CCC(CC1)c1c[nH]c2ccccc12 Show InChI InChI=1S/C23H35N3/c1-5-13-25(14-6-1)15-7-2-8-16-26-17-11-20(12-18-26)22-19-24-23-10-4-3-9-21(22)23/h3-4,9-10,19-20,24H,1-2,5-8,11-18H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. Curated by ChEMBL					Assay Description Binding affinity to human adrenergic Alpha-1D receptor				Bioorg Med Chem Lett 16: 4045-7 (2006) Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50187747 (3-(1-(5-(piperidin-1-yl)pentyl)piperidin-4-yl)-1H-...) Show SMILES C(CCN1CCCCC1)CCN1CCC(CC1)c1c[nH]c2ccccc12 Show InChI InChI=1S/C23H35N3/c1-5-13-25(14-6-1)15-7-2-8-16-26-17-11-20(12-18-26)22-19-24-23-10-4-3-9-21(22)23/h3-4,9-10,19-20,24H,1-2,5-8,11-18H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes				Bioorg Med Chem Lett 16: 4045-7 (2006) Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001
					More data for this Ligand-Target Pair