BDBM50187758 5-(4-ethoxyphenyl)-7-(4-fluorobenzyl)-6H-pyrrolo[3,4-g]quinolin-8(7H)-one::7-(4-fluorobenzyl)-5-(4-ethoxyphenyl)-9-hydroxy-6,7-dihydropyrrolo[3,4-g]quinolin-8-one::CHEMBL377693

SMILES: CCOc1ccc(cc1)-c1c2CN(Cc3ccc(F)cc3)C(=O)c2c(O)c2ncccc12

InChI Key: InChIKey=SWIBQBSOVYGWFN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187758   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrase (Human immunodeficiency virus 1)	BDBM50187758 (5-(4-ethoxyphenyl)-7-(4-fluorobenzyl)-6H-pyrrolo[3...) Show SMILES CCOc1ccc(cc1)-c1c2CN(Cc3ccc(F)cc3)C(=O)c2c(O)c2ncccc12 Show InChI InChI=1S/C26H21FN2O3/c1-2-32-19-11-7-17(8-12-19)22-20-4-3-13-28-24(20)25(30)23-21(22)15-29(26(23)31)14-16-5-9-18(27)10-6-16/h3-13,30H,2,14-15H2,1H3	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Cyprus Curated by ChEMBL					Assay Description Inhibition of HIV1 integrase strand transfer activity				Bioorg Med Chem 17: 4806-18 (2009) Article DOI: 10.1016/j.bmc.2009.04.058 BindingDB Entry DOI: 10.7270/Q2R49TKS
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50187758 (5-(4-ethoxyphenyl)-7-(4-fluorobenzyl)-6H-pyrrolo[3...) Show SMILES CCOc1ccc(cc1)-c1c2CN(Cc3ccc(F)cc3)C(=O)c2c(O)c2ncccc12 Show InChI InChI=1S/C26H21FN2O3/c1-2-32-19-11-7-17(8-12-19)22-20-4-3-13-28-24(20)25(30)23-21(22)15-29(26(23)31)14-16-5-9-18(27)10-6-16/h3-13,30H,2,14-15H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Inhibition of strand transfer activity of HIV integrase				Bioorg Med Chem Lett 16: 3989-92 (2006) Article DOI: 10.1016/j.bmcl.2006.05.016 BindingDB Entry DOI: 10.7270/Q29K49T8
					More data for this Ligand-Target Pair