Found 5 hits for monomerid = 50187790 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Matrix metalloproteinase-14 (MMP14)
(Homo sapiens (Human)) | BDBM50187790
(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-hexa...)Show SMILES CCCCCC(=O)N1CCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(CC1)C(=O)NO Show InChI InChI=1S/C23H32N2O6S/c1-3-5-7-8-21(26)25-15-13-23(14-16-25,22(27)24-28)18-32(29,30)20-11-9-19(10-12-20)31-17-6-4-2/h9-12,28H,3,5,7-8,13-18H2,1-2H3,(H,24,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of MMP14 |
Bioorg Med Chem Lett 16: 3927-31 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.026 BindingDB Entry DOI: 10.7270/Q2222TCJ |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50187790
(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-hexa...)Show SMILES CCCCCC(=O)N1CCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(CC1)C(=O)NO Show InChI InChI=1S/C23H32N2O6S/c1-3-5-7-8-21(26)25-15-13-23(14-16-25,22(27)24-28)18-32(29,30)20-11-9-19(10-12-20)31-17-6-4-2/h9-12,28H,3,5,7-8,13-18H2,1-2H3,(H,24,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
Bioorg Med Chem Lett 16: 3927-31 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.026 BindingDB Entry DOI: 10.7270/Q2222TCJ |
More data for this Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50187790
(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-hexa...)Show SMILES CCCCCC(=O)N1CCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(CC1)C(=O)NO Show InChI InChI=1S/C23H32N2O6S/c1-3-5-7-8-21(26)25-15-13-23(14-16-25,22(27)24-28)18-32(29,30)20-11-9-19(10-12-20)31-17-6-4-2/h9-12,28H,3,5,7-8,13-18H2,1-2H3,(H,24,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of MMP1 |
Bioorg Med Chem Lett 16: 3927-31 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.026 BindingDB Entry DOI: 10.7270/Q2222TCJ |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50187790
(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-hexa...)Show SMILES CCCCCC(=O)N1CCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(CC1)C(=O)NO Show InChI InChI=1S/C23H32N2O6S/c1-3-5-7-8-21(26)25-15-13-23(14-16-25,22(27)24-28)18-32(29,30)20-11-9-19(10-12-20)31-17-6-4-2/h9-12,28H,3,5,7-8,13-18H2,1-2H3,(H,24,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 553 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
Bioorg Med Chem Lett 16: 3927-31 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.026 BindingDB Entry DOI: 10.7270/Q2222TCJ |
More data for this Ligand-Target Pair | |
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human)) | BDBM50187790
(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-hexa...)Show SMILES CCCCCC(=O)N1CCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(CC1)C(=O)NO Show InChI InChI=1S/C23H32N2O6S/c1-3-5-7-8-21(26)25-15-13-23(14-16-25,22(27)24-28)18-32(29,30)20-11-9-19(10-12-20)31-17-6-4-2/h9-12,28H,3,5,7-8,13-18H2,1-2H3,(H,24,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of TACE by FRET assay |
Bioorg Med Chem Lett 16: 3927-31 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.026 BindingDB Entry DOI: 10.7270/Q2222TCJ |
More data for this Ligand-Target Pair | |