BindingDB logo
myBDB logout

BDBM50187926 1-(3-(3-(pyrrolidin-1-yl)propoxy)phenyl)-3-(3-(trifluoromethyl)phenylimino)indolin-2-one::CHEMBL211031

SMILES: FC(F)(F)c1cccc(c1)\N=C1\C(=O)N(c2ccccc12)c1cccc(OCCCN2CCCC2)c1

InChI Key: InChIKey=NUADTUZMPQSMJY-HMZBKAONSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187926   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Galanin receptor 3


(Homo sapiens (Human))		BDBM50187926
PNG
(1-(3-(3-(pyrrolidin-1-yl)propoxy)phenyl)-3-(3-(tri...)
Show SMILES FC(F)(F)c1cccc(c1)\N=C1\C(=O)N(c2ccccc12)c1cccc(OCCCN2CCCC2)c1
Show InChI InChI=1S/C28H26F3N3O2/c29-28(30,31)20-8-5-9-21(18-20)32-26-24-12-1-2-13-25(24)34(27(26)35)22-10-6-11-23(19-22)36-17-7-16-33-14-3-4-15-33/h1-2,5-6,8-13,18-19H,3-4,7,14-17H2/b32-26+
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 49n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]galanin from human galanin Gal3 receptor

Bioorg Med Chem Lett 16: 3950-4 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.025
BindingDB Entry DOI: 10.7270/Q2DB81F2
More data for this
Ligand-Target Pair