BDBM50188060 1-(1-phenyl-2-(2-(trifluoromethyl)phenyl)ethyl)piperazine::CHEMBL210027

SMILES: FC(F)(F)c1ccccc1CC(N1CCNCC1)c1ccccc1

InChI Key: InChIKey=MQGLAASXHMCXDS-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50188060   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50188060 (1-(1-phenyl-2-(2-(trifluoromethyl)phenyl)ethyl)pip...) Show SMILES FC(F)(F)c1ccccc1CC(N1CCNCC1)c1ccccc1 Show InChI InChI=1S/C19H21F3N2/c20-19(21,22)17-9-5-4-8-16(17)14-18(15-6-2-1-3-7-15)24-12-10-23-11-13-24/h1-9,18,23H,10-14H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake at 5HT transporter expressed in HEK293 cells				Bioorg Med Chem Lett 16: 4345-8 (2006) Article DOI: 10.1016/j.bmcl.2006.05.051 BindingDB Entry DOI: 10.7270/Q2H99608
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50188060 (1-(1-phenyl-2-(2-(trifluoromethyl)phenyl)ethyl)pip...) Show SMILES FC(F)(F)c1ccccc1CC(N1CCNCC1)c1ccccc1 Show InChI InChI=1S/C19H21F3N2/c20-19(21,22)17-9-5-4-8-16(17)14-18(15-6-2-1-3-7-15)24-12-10-23-11-13-24/h1-9,18,23H,10-14H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]NA uptake at NA transporter expressed in HEK293 cells				Bioorg Med Chem Lett 16: 4345-8 (2006) Article DOI: 10.1016/j.bmcl.2006.05.051 BindingDB Entry DOI: 10.7270/Q2H99608
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50188060 (1-(1-phenyl-2-(2-(trifluoromethyl)phenyl)ethyl)pip...) Show SMILES FC(F)(F)c1ccccc1CC(N1CCNCC1)c1ccccc1 Show InChI InChI=1S/C19H21F3N2/c20-19(21,22)17-9-5-4-8-16(17)14-18(15-6-2-1-3-7-15)24-12-10-23-11-13-24/h1-9,18,23H,10-14H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of DA transporter expressed in HEK293 cells				Bioorg Med Chem Lett 16: 4345-8 (2006) Article DOI: 10.1016/j.bmcl.2006.05.051 BindingDB Entry DOI: 10.7270/Q2H99608
					More data for this Ligand-Target Pair