BDBM50188086 4-((1H-imidazol-1-yl)methyl)phenol::4-Imidazol-1-ylmethyl-phenol::CHEMBL166845
SMILES: Oc1ccc(Cn2ccnc2)cc1
InChI Key: InChIKey=ZEFROCQEWXHIEP-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 17A1 (Rattus norvegicus (Rat)) | BDBM50188086 (4-((1H-imidazol-1-yl)methyl)phenol | 4-Imidazol-1-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University Curated by ChEMBL | Assay Description Inhibition of rat microsomal 17,20-lyase component of P450-17alpha | Bioorg Med Chem Lett 16: 4011-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.070 BindingDB Entry DOI: 10.7270/Q27M07J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 17A1 (Rattus norvegicus (Rat)) | BDBM50188086 (4-((1H-imidazol-1-yl)methyl)phenol | 4-Imidazol-1-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland Curated by ChEMBL | Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha | Bioorg Med Chem Lett 20: 5345-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.100 BindingDB Entry DOI: 10.7270/Q2DF6RF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 17A1 (Rattus norvegicus (Rat)) | BDBM50188086 (4-((1H-imidazol-1-yl)methyl)phenol | 4-Imidazol-1-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland Curated by ChEMBL | Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha | Bioorg Med Chem Lett 20: 5345-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.100 BindingDB Entry DOI: 10.7270/Q2DF6RF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 17A1 (Rattus norvegicus (Rat)) | BDBM50188086 (4-((1H-imidazol-1-yl)methyl)phenol | 4-Imidazol-1-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University Curated by ChEMBL | Assay Description Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alpha | Bioorg Med Chem Lett 16: 4011-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.070 BindingDB Entry DOI: 10.7270/Q27M07J2 | |||||||||||
More data for this Ligand-Target Pair |