BDBM50188922 4-(5-((2,4-dichlorophenethylamino)methyl)thiophen-2-yl)-N-methylpyrimidin-2-amine::CHEMBL214906

SMILES: CNc1nccc(n1)-c1ccc(CNCCc2ccc(Cl)cc2Cl)s1

InChI Key: InChIKey=VGIACESEDZYOSI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188922   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase AKT (Homo sapiens (Human))	BDBM50188922 (4-(5-((2,4-dichlorophenethylamino)methyl)thiophen-...) Show SMILES CNc1nccc(n1)-c1ccc(CNCCc2ccc(Cl)cc2Cl)s1 Show InChI InChI=1S/C18H18Cl2N4S/c1-21-18-23-9-7-16(24-18)17-5-4-14(25-17)11-22-8-6-12-2-3-13(19)10-15(12)20/h2-5,7,9-10,22H,6,8,11H2,1H3,(H,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibition of AKT3 in presence of 0.2 uM ATP				Bioorg Med Chem Lett 16: 4163-8 (2006) Article DOI: 10.1016/j.bmcl.2006.05.092 BindingDB Entry DOI: 10.7270/Q24M945C
					More data for this Ligand-Target Pair