BDBM50188933 CHEMBL209952::N-((S)-2-amino-2-(2,4-dichlorophenyl)ethyl)-5-(2-(methylamino)pyrimidin-4-yl)thiophene-2-carboxamide

SMILES: CNc1nccc(n1)-c1ccc(s1)C(=O)NC[C@@H](N)c1ccc(Cl)cc1Cl

InChI Key: InChIKey=ATAKSXFUGITJML-CYBMUJFWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188933   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase AKT (Homo sapiens (Human))	BDBM50188933 (CHEMBL209952 | N-((S)-2-amino-2-(2,4-dichloropheny...) Show SMILES CNc1nccc(n1)-c1ccc(s1)C(=O)NC[C@@H](N)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C18H17Cl2N5OS/c1-22-18-23-7-6-14(25-18)15-4-5-16(27-15)17(26)24-9-13(21)11-3-2-10(19)8-12(11)20/h2-8,13H,9,21H2,1H3,(H,24,26)(H,22,23,25)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibition of AKT3 in presence of 0.2 uM ATP				Bioorg Med Chem Lett 16: 4163-8 (2006) Article DOI: 10.1016/j.bmcl.2006.05.092 BindingDB Entry DOI: 10.7270/Q24M945C
					More data for this Ligand-Target Pair