BDBM50189030 4-chloro-N-(2,5-difluorophenyl)-N-(1-(2-(3-(piperidin-1-yl)propoxy)phenyl)ethyl)benzenesulfonamide::CHEMBL209739

SMILES: CC(N(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1)c1ccccc1OCCCN1CCCCC1

InChI Key: InChIKey=WSACYBAWHVTHKU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50189030   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-Secretase Subunit APH-1A/Gamma-Secretase Subunit PEN-2/Gamma-Secretase Subunit Presenilin-1/Gamma-secretase subunit APH-1B/Nicastrin /Presenilin 2 (Homo sapiens (Human))	BDBM50189030 (4-chloro-N-(2,5-difluorophenyl)-N-(1-(2-(3-(piperi...) Show SMILES CC(N(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1)c1ccccc1OCCCN1CCCCC1 Show InChI InChI=1S/C28H31ClF2N2O3S/c1-21(25-8-3-4-9-28(25)36-19-7-18-32-16-5-2-6-17-32)33(27-20-23(30)12-15-26(27)31)37(34,35)24-13-10-22(29)11-14-24/h3-4,8-15,20-21H,2,5-7,16-19H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
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