BDBM50189040 4-chloro-N-(4-chlorophenyl)-N-(1-(2-(3-(pyrrolidin-1-yl)propoxy)phenyl)ethyl)benzenesulfonamide::CHEMBL213557

SMILES: CC(N(c1ccc(Cl)cc1)S(=O)(=O)c1ccc(Cl)cc1)c1ccccc1OCCCN1CCCC1

InChI Key: InChIKey=GVQOZPIUVJHSCK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50189040   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-Secretase Subunit APH-1A/Gamma-Secretase Subunit PEN-2/Gamma-Secretase Subunit Presenilin-1/Gamma-secretase subunit APH-1B/Nicastrin /Presenilin 2 (Homo sapiens (Human))	BDBM50189040 (4-chloro-N-(4-chlorophenyl)-N-(1-(2-(3-(pyrrolidin...) Show SMILES CC(N(c1ccc(Cl)cc1)S(=O)(=O)c1ccc(Cl)cc1)c1ccccc1OCCCN1CCCC1 Show InChI InChI=1S/C27H30Cl2N2O3S/c1-21(26-7-2-3-8-27(26)34-20-6-19-30-17-4-5-18-30)31(24-13-9-22(28)10-14-24)35(32,33)25-15-11-23(29)12-16-25/h2-3,7-16,21H,4-6,17-20H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Inhibition of beta amyloid protein 40 production				Bioorg Med Chem Lett 16: 4184-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.091 BindingDB Entry DOI: 10.7270/Q2RF5TN8
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