BDBM50189240 (R)-2-(2-(4-methoxyphenyl)furan-5-carboxamido)-3-(3,7,11-trimethyldodeca-2,6,10-trienylthio)propanoic acid::CHEMBL213243
SMILES: [#6]-[#8]-c1ccc(cc1)-c1ccc(o1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#16]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6](-[#8])=O
InChI Key: InChIKey=FKXMLKCACUZGFO-PLFWPOPISA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Isoprenylcysteine carboxyl methyltransferase (Homo sapiens (Human)) | BDBM50189240 ((R)-2-(2-(4-methoxyphenyl)furan-5-carboxamido)-3-(...) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.74E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of human Icmt by methanol vapour diffusion assay | Bioorg Med Chem Lett 16: 4420-3 (2006) Article DOI: 10.1016/j.bmcl.2006.05.029 BindingDB Entry DOI: 10.7270/Q27D2TRG | |||||||||||
More data for this Ligand-Target Pair |