BDBM50189292 CHEMBL3828157

SMILES: CCOC(=O)c1cc(C(=O)\C=C\c2ccc3N(C)c4ccccc4Sc3c2)n2ccccc12

InChI Key: InChIKey=DEBGEDXBSMFDAS-WYMLVPIESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50189292   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50189292 (CHEMBL3828157) Show SMILES CCOC(=O)c1cc(C(=O)\C=C\c2ccc3N(C)c4ccccc4Sc3c2)n2ccccc12 Show InChI InChI=1S/C27H22N2O3S/c1-3-32-27(31)19-17-23(29-15-7-6-8-20(19)29)24(30)14-12-18-11-13-22-26(16-18)33-25-10-5-4-9-21(25)28(22)2/h4-17H,3H2,1-2H3/b14-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...				Bioorg Med Chem Lett 26: 3730-4 (2016) BindingDB Entry DOI: 10.7270/Q2DR2XFP
					More data for this Ligand-Target Pair