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BDBM50189584 (R)-6-(4-chlorophenyl)-2-(6-(3-(dimethylamino)pyrrolidin-1-yl)pyridin-3-yl)phthalazin-1(2H)-one::CHEMBL379189

SMILES: CN(C)[C@@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(ccc2c1=O)-c1ccc(Cl)cc1

InChI Key: InChIKey=LQVKFCWAMKNRJH-JOCHJYFZSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50189584   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
GPR24


(RAT)		BDBM50189584
PNG
((R)-6-(4-chlorophenyl)-2-(6-(3-(dimethylamino)pyrr...)
Show SMILES CN(C)[C@@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(ccc2c1=O)-c1ccc(Cl)cc1
Show InChI InChI=1S/C25H24ClN5O/c1-29(2)22-11-12-30(16-22)24-10-8-21(15-27-24)31-25(32)23-9-5-18(13-19(23)14-28-31)17-3-6-20(26)7-4-17/h3-10,13-15,22H,11-12,16H2,1-2H3/t22-/m1/s1
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Similars
Article
PubMed
 1.10n/an/an/an/an/an/an/an/a



Neurocrine Biosciences Inc.

Curated by ChEMBL


Assay Description
Binding affinity to chimeric rat/human MCH1R stably expressed in HEK293 cells

J Med Chem 49: 3753-6 (2006)


Article DOI: 10.1021/jm051263c
BindingDB Entry DOI: 10.7270/Q2Z037SN
More data for this
Ligand-Target Pair