BDBM50189609 CHEMBL209555::N-cyclopropyl-4-fluoro-3-(2-(2-(pyridin-2-ylamino)thiazol-5-yl)ethyl)benzamide
SMILES: Fc1ccc(cc1CCc1cnc(Nc2ccccn2)s1)C(=O)NC1CC1
InChI Key: InChIKey=CMTFYUMOJRAUPR-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50189609 (CHEMBL209555 | N-cyclopropyl-4-fluoro-3-(2-(2-(pyr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of FLK1 | J Med Chem 49: 3766-9 (2006) Article DOI: 10.1021/jm060347y BindingDB Entry DOI: 10.7270/Q2PG1RBM | |||||||||||
More data for this Ligand-Target Pair |