BDBM50189777 CHEMBL212815::N-tert-butyl-5-amino-4-(3-fluorophenyl)-2-(methylthio)thieno[2,3-d]pyrimidine-6-carboxamide

SMILES: CSc1nc(-c2cccc(F)c2)c2c(N)c(sc2n1)C(=O)NC(C)(C)C

InChI Key: InChIKey=RDGDTXHTCFMEPO-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50189777   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human))	BDBM50189777 (CHEMBL212815 | N-tert-butyl-5-amino-4-(3-fluorophe...) Show SMILES CSc1nc(-c2cccc(F)c2)c2c(N)c(sc2n1)C(=O)NC(C)(C)C Show InChI InChI=1S/C18H19FN4OS2/c1-18(2,3)23-15(24)14-12(20)11-13(9-6-5-7-10(19)8-9)21-17(25-4)22-16(11)26-14/h5-8H,20H2,1-4H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Agonist activity at LHCGR expressed in HEK293 EM cells measured by intracellular cAMP accumulation				J Med Chem 49: 3888-96 (2006) Article DOI: 10.1021/jm060247s BindingDB Entry DOI: 10.7270/Q29886MR
					More data for this Ligand-Target Pair