BDBM50190227 CHEMBL213444::quinoline-3-carboxylic acid [8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-amide

SMILES: CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2cnc3ccccc3c2)c2ccccc12

InChI Key: InChIKey=AIHMNABLEMTJJF-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190227   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50190227 (CHEMBL213444 | quinoline-3-carboxylic acid [8-chlo...) Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2cnc3ccccc3c2)c2ccccc12 |t:8| Show InChI InChI=1S/C28H25ClN6O/c1-33-12-14-34(15-13-33)27-22-7-3-5-9-25(22)35(26-11-10-21(29)17-24(26)31-27)32-28(36)20-16-19-6-2-4-8-23(19)30-18-20/h2-11,16-18H,12-15H2,1H3,(H,32,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from human dopamine D1 receptor expressed in CHO cells				Bioorg Med Chem Lett 16: 4543-7 (2006) Article DOI: 10.1016/j.bmcl.2006.06.022 BindingDB Entry DOI: 10.7270/Q2GT5MSW
					More data for this Ligand-Target Pair