BDBM50190742 (S)-2-((1-((5-methyl-1,3,4-thiadiazol-2-yl)carbamoyl)cyclopentyl)methyl)pentanoic acid::CHEMBL211450

SMILES: CCC[C@@H](CC1(CCCC1)C(=O)Nc1nnc(C)s1)C(O)=O

InChI Key: InChIKey=FEIWTOVFMGPLGF-NSHDSACASA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190742   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM50190742 ((S)-2-((1-((5-methyl-1,3,4-thiadiazol-2-yl)carbamo...) Show SMILES CCC[C@@H](CC1(CCCC1)C(=O)Nc1nnc(C)s1)C(O)=O Show InChI InChI=1S/C15H23N3O3S/c1-3-6-11(12(19)20)9-15(7-4-5-8-15)13(21)16-14-18-17-10(2)22-14/h11H,3-9H2,1-2H3,(H,19,20)(H,16,18,21)/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	286	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50190742 ((S)-2-((1-((5-methyl-1,3,4-thiadiazol-2-yl)carbamo...) Show SMILES CCC[C@@H](CC1(CCCC1)C(=O)Nc1nnc(C)s1)C(O)=O Show InChI InChI=1S/C15H23N3O3S/c1-3-6-11(12(19)20)9-15(7-4-5-8-15)13(21)16-14-18-17-10(2)22-14/h11H,3-9H2,1-2H3,(H,19,20)(H,16,18,21)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog ACE				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair