BDBM50190889 2-(6-(3-cyanophenyl)-1-(1-cycloheptylpiperidin-4-yl)-3,4-dihydroisoquinolin-2(1H)-yl)-N-(3,5-dichlorophenyl)acetamide::CHEMBL408332

SMILES: Clc1cc(Cl)cc(NC(=O)CN2CCc3cc(ccc3C2C2CCN(CC2)C2CCCCCC2)-c2cccc(c2)C#N)c1

InChI Key: InChIKey=SDCCZLAUOPATRC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190889   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50190889 (2-(6-(3-cyanophenyl)-1-(1-cycloheptylpiperidin-4-y...) Show SMILES Clc1cc(Cl)cc(NC(=O)CN2CCc3cc(ccc3C2C2CCN(CC2)C2CCCCCC2)-c2cccc(c2)C#N)c1 Show InChI InChI=1S/C36H40Cl2N4O/c37-30-20-31(38)22-32(21-30)40-35(43)24-42-17-14-29-19-28(27-7-5-6-25(18-27)23-39)10-11-34(29)36(42)26-12-15-41(16-13-26)33-8-3-1-2-4-9-33/h5-7,10-11,18-22,26,33,36H,1-4,8-9,12-17,24H2,(H,40,43)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity to human MCHR1				Bioorg Med Chem Lett 16: 4917-21 (2006) Article DOI: 10.1016/j.bmcl.2006.06.055 BindingDB Entry DOI: 10.7270/Q2WW7H83
					More data for this Ligand-Target Pair