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SMILES: Fc1ccc(cc1)-n1nc(C(=O)Nc2ccc(Oc3ccncc3-c3cccnc3)c(F)c2)c2ccccc2c1=O

InChI Key: InChIKey=IDBCNFQMNXIEAQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190916   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50190916
PNG
(CHEMBL3894838)
Show SMILES Fc1ccc(cc1)-n1nc(C(=O)Nc2ccc(Oc3ccncc3-c3cccnc3)c(F)c2)c2ccccc2c1=O
Show InChI InChI=1S/C31H19F2N5O3/c32-20-7-10-22(11-8-20)38-31(40)24-6-2-1-5-23(24)29(37-38)30(39)36-21-9-12-28(26(33)16-21)41-27-13-15-35-18-25(27)19-4-3-14-34-17-19/h1-18H,(H,36,39)
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PC cid
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Similars
PubMed
n/an/a 52n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay

Eur J Med Chem 120: 37-50 (2016)


BindingDB Entry DOI: 10.7270/Q2VM4F5Q
More data for this
Ligand-Target Pair