BDBM50191173 1-(2-methylpropyl)-4'-(pyridin-4-yl)-8'-oxa-5',6'-diazaspiro[piperidine-4,7'-tricyclo[7.4.0.0^{2,6}]tridecane]-1'(13'),4',9',11'-tetraene::CHEMBL384160

SMILES: CC(C)CN1CCC2(CC1)Oc1ccccc1C1CC(=NN21)c1ccncc1

InChI Key: InChIKey=IQWJWMITZOKUAX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191173   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50191173 (1-(2-methylpropyl)-4'-(pyridin-4-yl)-8'-oxa-5',6'-...) Show SMILES CC(C)CN1CCC2(CC1)Oc1ccccc1C1CC(=NN21)c1ccncc1 |c:21| Show InChI InChI=1S/C23H28N4O/c1-17(2)16-26-13-9-23(10-14-26)27-21(19-5-3-4-6-22(19)28-23)15-20(25-27)18-7-11-24-12-8-18/h3-8,11-12,17,21H,9-10,13-16H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Hopital Saint-Louis Curated by ChEMBL					Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release				Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X
					More data for this Ligand-Target Pair