BDBM50191179 1-(2-phenylethyl)-4'-(pyridin-4-yl)-8'-oxa-5',6'-diazaspiro[piperidine-4,7'-tricyclo[7.4.0.0^{2,6}]tridecane]-1'(13'),4',9',11'-tetraene::CHEMBL383860

SMILES: C(Cc1ccccc1)N1CCC2(CC1)Oc1ccccc1C1CC(=NN21)c1ccncc1

InChI Key: InChIKey=UDGRDEHNLPZGFP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191179   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50191179 (1-(2-phenylethyl)-4'-(pyridin-4-yl)-8'-oxa-5',6'-d...) Show SMILES C(Cc1ccccc1)N1CCC2(CC1)Oc1ccccc1C1CC(=NN21)c1ccncc1 |c:26| Show InChI InChI=1S/C27H28N4O/c1-2-6-21(7-3-1)12-17-30-18-13-27(14-19-30)31-25(23-8-4-5-9-26(23)32-27)20-24(29-31)22-10-15-28-16-11-22/h1-11,15-16,25H,12-14,17-20H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Hopital Saint-Louis Curated by ChEMBL					Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release				Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X
					More data for this Ligand-Target Pair