BDBM50191208 12'-bromo-4'-(4-fluorophenyl)-1-propyl-8'-oxa-5',6'-diazaspiro[piperidine-4,7'-tricyclo[7.4.0.0^{2,6}]tridecane]-1'(13'),4',9',11'-tetraene::CHEMBL213005

SMILES: CCCN1CCC2(CC1)Oc1ccc(Br)cc1C1CC(=NN21)c1ccc(F)cc1

InChI Key: InChIKey=HCPSFARKPCRFOB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191208   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50191208 (12'-bromo-4'-(4-fluorophenyl)-1-propyl-8'-oxa-5',6...) Show SMILES CCCN1CCC2(CC1)Oc1ccc(Br)cc1C1CC(=NN21)c1ccc(F)cc1 |c:21| Show InChI InChI=1S/C23H25BrFN3O/c1-2-11-27-12-9-23(10-13-27)28-21(19-14-17(24)5-8-22(19)29-23)15-20(26-28)16-3-6-18(25)7-4-16/h3-8,14,21H,2,9-13,15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Hopital Saint-Louis Curated by ChEMBL					Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release				Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X
					More data for this Ligand-Target Pair