BDBM50191545 2-[4-(4-Chlorobiphenyl-2-ylmethoxy)phenyl]-1-cyclohexyl-1H-benzimidazole-5-carboxylic acid::CHEMBL212677

SMILES: OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc(OCc2cc(Cl)ccc2-c2ccccc2)cc1

InChI Key: InChIKey=PWRLOTKPLAEFHN-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50191545   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50191545 (2-[4-(4-Chlorobiphenyl-2-ylmethoxy)phenyl]-1-cyclo...) Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc(OCc2cc(Cl)ccc2-c2ccccc2)cc1 Show InChI InChI=1S/C33H29ClN2O3/c34-26-14-17-29(22-7-3-1-4-8-22)25(19-26)21-39-28-15-11-23(12-16-28)32-35-30-20-24(33(37)38)13-18-31(30)36(32)27-9-5-2-6-10-27/h1,3-4,7-8,11-20,27H,2,5-6,9-10,21H2,(H,37,38)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of HCV 1b BK six His-tagged C-terminal truncated 544 amino acid NS5B RNA dependent RNA polymerase				J Med Chem 49: 4721-36 (2006) Article DOI: 10.1021/jm060269e BindingDB Entry DOI: 10.7270/Q2FN15TD
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus genotype 1)	BDBM50191545 (2-[4-(4-Chlorobiphenyl-2-ylmethoxy)phenyl]-1-cyclo...) Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc(OCc2cc(Cl)ccc2-c2ccccc2)cc1 Show InChI InChI=1S/C33H29ClN2O3/c34-26-14-17-29(22-7-3-1-4-8-22)25(19-26)21-39-28-15-11-23(12-16-28)32-35-30-20-24(33(37)38)13-18-31(30)36(32)27-9-5-2-6-10-27/h1,3-4,7-8,11-20,27H,2,5-6,9-10,21H2,(H,37,38)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 min				Citation and Details Article DOI: 10.1007/s00044-012-0186-8 BindingDB Entry DOI: 10.7270/Q2NC6441
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus genotype 1)	BDBM50191545 (2-[4-(4-Chlorobiphenyl-2-ylmethoxy)phenyl]-1-cyclo...) Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc(OCc2cc(Cl)ccc2-c2ccccc2)cc1 Show InChI InChI=1S/C33H29ClN2O3/c34-26-14-17-29(22-7-3-1-4-8-22)25(19-26)21-39-28-15-11-23(12-16-28)32-35-30-20-24(33(37)38)13-18-31(30)36(32)27-9-5-2-6-10-27/h1,3-4,7-8,11-20,27H,2,5-6,9-10,21H2,(H,37,38)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	5.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 min				Citation and Details Article DOI: 10.1007/s00044-012-0186-8 BindingDB Entry DOI: 10.7270/Q2NC6441
					More data for this Ligand-Target Pair